About me
Methods for Precise Oncology Interventions in Nutrition and Training (OnPOINT) Trial: A Lifestyle Complexity Stratification Model for Cancer Survivors
Location: 94
Mentor: Dr. Harleen Kaur
Lifestyle behaviors can reduce the risk of cancer recurrence and mitigate comorbid conditions among cancer survivors. However, individual needs for nutrition and exercise programs may vary. The purpose of the OnPOINT trial is to evaluate the feasibility, acceptability, and retention of a stratified nutrition and exercise referral programs for cancer survivors. The OnPOINT study is a two-arm randomized controlled trial that aims to enroll 300 breast, prostate, and colorectal cancer survivors who are at least six months post-treatment for their primary cancer. Eligible participants are randomized into either an 8-week virtual intervention or control arm. The 8-week virtual intervention is tailored to the unique needs of cancer survivors through a complexity stratification algorithm, which assigns participants to low, moderate, or high complexity nutrition and exercise programs. This complexity stratification algorithm integrates a range of demographic, medical, physical, environmental, and psychosocial factors, informed from clinical data obtained via EPIC electronic health records and patient-reported data from questionnaires. Enrollment commenced in September 2024. To date, 145 cancer survivors have been screened, with 22 currently enrolled in the study. The average age of those enrolled is 58 years, and the majority are non-Hispanic female breast cancer survivors. Full accrual is anticipated by Summer 2025. There is a need for tailored nutrition and exercise programs for cancer survivors. The OnPOINT study aims to evaluate the feasibility of implementing a complexity stratification model in clinical settings to improve nutrition and exercise referrals, with the goal of evaluating sustainable and impactful lifestyle programs for cancer survivors.
