About me
mCARES–H: An HIV Intervention, Utilizing Novel Bio – Markers to Measure Anti - Retroviral Levels
Location: 74
Mentor: Dr. Lunthita Duthely
Introduction: Poor adherence to antiretroviral therapy (ARV) among women with HIV has been associated with negative health outcomes, including increased HIV viral load, other medical co - morbidities, and complications with long – term HIV care. Traditional blood tests to monitor adherence are often inconvenient and may not reflect long-term patterns.
Purpose: This research study investigates the feasibility of using home-based, small hair samples to measure ARV levels in a diverse group of women living in South Florida, an epicenter for HIV.
Method(s): The study employs a mixed-methods design, consisting of two parts. Part 1 involves a pilot phase with 3-5 participants to refine the hair collection process and gather feedback. In Part 2, participants from a South Florida clinic, at risk for discontinuing care, are recruited to self-collect hair samples at home, which are mailed to a laboratory for analysis. Participants also complete surveys assessing demographic, psychosocial factors, and HIV health outcomes.
Results: Preliminary results show that most participants agreed to participate, with nine samples mailed to the lab, of which seven were successfully received. However, participants encountered challenges, such as difficulty cutting hair and finding mailing locations.
Conclusion/Implications: Despite these issues, the feasibility of hair sampling as an ARV adherence measure is promising, though further training and support may be needed for successful implementation. This research has the potential to offer a more convenient and accurate alternative to current ARV adherence monitoring methods, with implications for improving long-term HIV care, particularly among underserved women.
